Isochorismate pyruvate lyase: Difference between revisions
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==Conserved Residues== | ==Conserved Residues== | ||
5 amino acids that are conserved in the homologous protein 1ECM, which is a chorismate mutase are Arg14, Arg 31, Lys 42(disordered in the open structure), Arg 53 and Gln 90. There are 3 other residues that are not conserved in pchB, however (Tyr 86, Ala 50 and Val 54). | 5 amino acids that are conserved in the homologous protein 1ECM, which is a chorismate mutase are Arg14, Arg 31, Lys 42(disordered in the open structure), Arg 53 and Gln 90. There are 3 other residues that are not conserved in pchB, however (Tyr 86, Ala 50 and Val 54). | ||
[[Image:i87.png|300px| | [[Image:conservedinclosed.png|300px|center]] | ||
[[Image:i87.png|300px|left]] | |||
[[Image:native open.png|300px|left]] | [[Image:native open.png|300px|left]] | ||
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[[Image:hotpatchsmallmolattachment2h9c.png|300px|left]] | [[Image:hotpatchsmallmolattachment2h9c.png|300px|left]] | ||
==Correlation of structure with function== | ==Correlation of structure with function== | ||