Isochorismate pyruvate lyase: Difference between revisions
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The difference between the apo and the ligand bound open and close structures is in the ligand binding and the loop connecting the first and the second helix. In case of the open form, the loop is disordered and in case of the closed form it is ordered. The apo structure has nitrate ion in the active site (that is occupied by pyruvate) due to ammonium nitrate reservoir buffer during crystallization. | The difference between the apo and the ligand bound open and close structures is in the ligand binding and the loop connecting the first and the second helix. In case of the open form, the loop is disordered and in case of the closed form it is ordered. The apo structure has nitrate ion in the active site (that is occupied by pyruvate) due to ammonium nitrate reservoir buffer during crystallization. | ||
<applet load="2H9C" size="400" frame="true" align="right" /> | <applet load="2H9C" size="400" frame="true" align="right" /> | ||
[[Image:native open.png| | [[Image:native open.png|300px|left]] | ||