3d0e: Difference between revisions
New page: '''Unreleased structure''' The entry 3d0e is ON HOLD until Paper Publication Authors: Concha, N.O., Smallwood, A. Description: Crystal structure of human Akt2 in complex with GSK690693... |
No edit summary |
||
| Line 1: | Line 1: | ||
{{Seed}} | |||
[[Image:3d0e.jpg|left|200px]] | |||
The | <!-- | ||
The line below this paragraph, containing "STRUCTURE_3d0e", creates the "Structure Box" on the page. | |||
You may change the PDB parameter (which sets the PDB file loaded into the applet) | |||
or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |||
or leave the SCENE parameter empty for the default display. | |||
--> | |||
{{STRUCTURE_3d0e| PDB=3d0e | SCENE= }} | |||
===Crystal structure of human Akt2 in complex with GSK690693=== | |||
<!-- | |||
The line below this paragraph, {{ABSTRACT_PUBMED_18800763}}, adds the Publication Abstract to the page | |||
(as it appears on PubMed at http://www.pubmed.gov), where 18800763 is the PubMed ID number. | |||
--> | |||
{{ABSTRACT_PUBMED_18800763}} | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | ==Disease== | ||
Known disease associated with this structure: Diabetes mellitus, type II OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164731 164731]] | |||
==About this Structure== | |||
3D0E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D0E OCA]. | |||
==Reference== | |||
Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]o xy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase., Heerding DA, Rhodes N, Leber JD, Clark TJ, Keenan RM, Lafrance LV, Li M, Safonov IG, Takata DT, Venslavsky JW, Yamashita DS, Choudhry AE, Copeland RA, Lai Z, Schaber MD, Tummino PJ, Strum SL, Wood ER, Duckett DR, Eberwein D, Knick VB, Lansing TJ, McConnell RT, Zhang S, Minthorn EA, Concha NO, Warren GL, Kumar R, J Med Chem. 2008 Sep 25;51(18):5663-79. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18800763 18800763] | |||
[[Category: Homo sapiens]] | |||
[[Category: Non-specific serine/threonine protein kinase]] | |||
[[Category: Single protein]] | |||
[[Category: Concha, N O.]] | |||
[[Category: Smallwood, A.]] | |||
[[Category: Akt2]] | |||
[[Category: Atp-binding]] | |||
[[Category: Human]] | |||
[[Category: Inhibitor]] | |||
[[Category: Kinase]] | |||
[[Category: Nucleotide-binding]] | |||
[[Category: Phosphoprotein]] | |||
[[Category: Polymorphism]] | |||
[[Category: Serine/threonine-protein kinase]] | |||
[[Category: Transferase]] | |||
[[Category: Transferase inhibitor]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 22 10:44:37 2008'' | |||
Revision as of 11:44, 22 October 2008
Crystal structure of human Akt2 in complex with GSK690693Crystal structure of human Akt2 in complex with GSK690693
Template:ABSTRACT PUBMED 18800763
DiseaseDisease
Known disease associated with this structure: Diabetes mellitus, type II OMIM:[164731]
About this StructureAbout this Structure
3D0E is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]o xy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase., Heerding DA, Rhodes N, Leber JD, Clark TJ, Keenan RM, Lafrance LV, Li M, Safonov IG, Takata DT, Venslavsky JW, Yamashita DS, Choudhry AE, Copeland RA, Lai Z, Schaber MD, Tummino PJ, Strum SL, Wood ER, Duckett DR, Eberwein D, Knick VB, Lansing TJ, McConnell RT, Zhang S, Minthorn EA, Concha NO, Warren GL, Kumar R, J Med Chem. 2008 Sep 25;51(18):5663-79. PMID:18800763
Page seeded by OCA on Wed Oct 22 10:44:37 2008