Lac repressor: Difference between revisions

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<applet load='1lbg' size='400' frame='true' align='right' scene='Lac_repressor/1lbg_lac_repressor_with_dna/1' />
<applet load='1lbg' size='400' frame='true' align='right' scene='Lac_repressor/1lbg_lac_repressor_with_dna/1' />


The lac repressor protein (<scene name='Lac_repressor/1lbg_lac_repressor_with_dna/1'>initial scene</scene>), starting at the N-terminus, begins with a <font color='red'><b>DNA-binding "headpiece"</b></font>, followed by a <font color='orange'><b>hinge region</b></font>, then an <font color='#00e080'><b>N-terminal ligand-binding subdomain</b></font> and a <font color='#20d0f0'><b>C-terminal ligand binding subdomain</b></font>, a <font color='#ff8080'><b>linker</b></font>, and a C-terminal <font color='#6060ff'><b>tetramerization helix</b></font><ref name='domaincolors'>This domain coloring scheme is adapted from Fig. 6 in the review by Lewis (''C. R. Biol.'')</ref>.
The lac repressor protein (<scene name='Lac_repressor/1lbg_lac_repressor_with_dna/1'>initial scene</scene>), starting at the N-terminus, begins with a <font color='red'><b>DNA-binding "headpiece"</b></font>, followed by a <font color='orange'><b>hinge region</b></font>, then an <font color='#00e080'><b>N-terminal ligand-binding subdomain</b></font> and a <font color='#20d0f0'><b>C-terminal ligand binding subdomain</b></font>, a <font color='#ff8080'><b>linker</b></font>, and a C-terminal <font color='#6060ff'><b>tetramerization helix</b></font><ref name='domaincolors'>This domain coloring scheme is adapted from Fig. 6 in the review by Lewis (''C. R. Biol.'' 328:521, 2005)</ref>.




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Eric Martz, Eran Hodis, David Canner, Michal Harel, Alexander Berchansky, Joel L. Sussman, Henry Jakubowski, Karsten Theis, Jaime Prilusky