Pyruvate phosphate dikinase: Difference between revisions
| Line 3: | Line 3: | ||
(this is a very preliminar page for [https://carb.umbi.umd.edu/herzberg/research Dr Osnat Herzberg]) | (this is a very preliminar page for [https://carb.umbi.umd.edu/herzberg/research Dr Osnat Herzberg]) | ||
<div style="float:right;padding:10px;"> | <div style="float:right;padding:10px;"> | ||
| <swf width="300" height="300">https://carb.umbi.umd.edu/system/files/ppdk_release.swf</swf><br> | | <swf width="300" height="300">https://carb.umbi.umd.edu/system/files/ppdk_release.swf</swf><br> | ||
You may also [https://carb.umbi.umd.edu/files/ppdk_release.mpg download] the full High Resolution video. | You may also [https://carb.umbi.umd.edu/files/ppdk_release.mpg download] the full High Resolution video. | ||
</div> | |||
Pyruvate phosphate dikinase (PPDK) catalyzes the inter-conversion of adenosine triphosphate (ATP), phosphate (P<sub>i</sub>), and pyruvate with adenine monophosphate (AMP), pyrophosphate (PP<sub>i</sub>), and phosphoenolpyruvate (PEP) in the presence of Mg<sup>2+</sup> and K<sup>+</sup>/Na<sup>+</sup>. The three-step reversible reaction proceeds via phosphoenzyme and pyrophosphoenzyme intermediates with a histidine residue serving as the phosphocarrier: | Pyruvate phosphate dikinase (PPDK) catalyzes the inter-conversion of adenosine triphosphate (ATP), phosphate (P<sub>i</sub>), and pyruvate with adenine monophosphate (AMP), pyrophosphate (PP<sub>i</sub>), and phosphoenolpyruvate (PEP) in the presence of Mg<sup>2+</sup> and K<sup>+</sup>/Na<sup>+</sup>. The three-step reversible reaction proceeds via phosphoenzyme and pyrophosphoenzyme intermediates with a histidine residue serving as the phosphocarrier: | ||