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| {{StructureC | | {{STRUCTURE_2hhdC | PDB=2hhd | SCENE= }} |
| |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|2hhd, resolution 2.20Å (<scene name='initialview01'>initial scene</scene>)}}} | |
| |LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
| |
| |DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01040 globin]</span>
| |
| |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hhd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hhd OCA], [http://www.ebi.ac.uk/pdbsum/2hhd PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2hhd RCSB]</span>
| |
| |FUNCTION={{GO|id=GO:0019825 | text = oxygen binding}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0005344 | text = oxygen transporter activity}}{{GO|id=GO:0020037 | text = heme binding}}{{GO|id=GO:0005506 | text = iron ion binding}}{{GO|id=GO:0030492 | text = hemoglobin binding}}{{GO|id=GO:0008430 | text = selenium binding}}
| |
| |PROCESS={{GO|id=GO:0006810 | text = transport}}{{GO|id=GO:0015671 | text = oxygen transport}}{{GO|id=GO:0045429 | text = positive regulation of nitric oxide biosynthetic process}}{{GO|id=GO:0030185 | text = nitric oxide transport}}{{GO|id=GO:0050880 | text = regulation of blood vessel size}}{{GO|id=GO:0008217 | text = regulation of blood pressure}}
| |
| |COMPONENT={{GO|id=GO:0005833 | text = hemoglobin complex}}
| |
| |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2hhdA00 2Hhda00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2hhdB00 2Hhdb00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2hhdC00 2Hhdc00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2hhdD00 2Hhdd00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002339 Ipr002339], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002338 Ipr002338], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000971 Ipr000971], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR009050 Ipr009050], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002337 Ipr002337], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR012292 Ipr012292]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00042 PF00042]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=15312 d2hhda_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=15489 d2hhdb_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=15313 d2hhdc_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=15490 d2hhdd_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P69905 P69905], [http://ca.expasy.org/cgi-bin/niceprot.pl?P68871 P68871]</span>
| |
| |FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=HBA1, HBA1,]</span>
| |
| |CONSURFLOCALANALYSIS={{!}}-
| |
| {{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
| |
| {{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
| |
| {{!}} '''Toggle Conservation Colors:'''
| |
| {{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
| |
| Rows = identical sequences:
| |
| | |
| <jmol>
| |
| <jmolButton>
| |
| <script>if (consurf_A!=0); select:A; spacefill off;color translucent -1;
| |
| consurf_A= 0;javascript "document.getElementById('jmb_A').value='A [ ]'";
| |
| else; select:A; spacefill on; color opaque;consurf_A = 1;javascript
| |
| "document.getElementById('jmb_A').value='A [x]';"; endif;</script>
| |
| <text>A [ ]</text>
| |
| <name>jmb_A</name>
| |
| </jmolButton>
| |
| </jmol>
| |
| <jmol>
| |
| <jmolButton>
| |
| <script>if (consurf_C!=0); select:C; spacefill off;color translucent -1;
| |
| consurf_C= 0;javascript "document.getElementById('jmb_C').value='C [ ]'";
| |
| else; select:C; spacefill on; color opaque;consurf_C = 1;javascript
| |
| "document.getElementById('jmb_C').value='C [x]';"; endif;</script>
| |
| <text>C [ ]</text>
| |
| <name>jmb_C</name>
| |
| </jmolButton>
| |
| </jmol>
| |
| | |
| <jmol>
| |
| <jmolButton>
| |
| <script>if (consurf_B!=0); select:B; spacefill off;color translucent -1;
| |
| consurf_B= 0;javascript "document.getElementById('jmb_B').value='B [ ]'";
| |
| else; select:B; spacefill on; color opaque;consurf_B = 1;javascript
| |
| "document.getElementById('jmb_B').value='B [x]';"; endif;</script>
| |
| <text>B [ ]</text>
| |
| <name>jmb_B</name>
| |
| </jmolButton>
| |
| </jmol>
| |
| <jmol>
| |
| <jmolButton>
| |
| <script>if (consurf_D!=0); select:D; spacefill off;color translucent -1;
| |
| consurf_D= 0;javascript "document.getElementById('jmb_D').value='D [ ]'";
| |
| else; select:D; spacefill on; color opaque;consurf_D = 1;javascript
| |
| "document.getElementById('jmb_D').value='D [x]';"; endif;</script>
| |
| <text>D [ ]</text>
| |
| <name>jmb_D</name>
| |
| </jmolButton>
| |
| </jmol>
| |
| | |
| {{!}}-
| |
| }} | |
