1u7c: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:
[[Image:1u7c.jpg|left|200px]]
{{Seed}}
[[Image:1u7c.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1u7c|  PDB=1u7c  |  SCENE=  }}  
{{STRUCTURE_1u7c|  PDB=1u7c  |  SCENE=  }}  


'''Crystal Structure of AmtB from E.Coli with Methyl Ammonium.'''
===Crystal Structure of AmtB from E.Coli with Methyl Ammonium.===




==Overview==
<!--
The first structure of an ammonia channel from the Amt/MEP/Rh protein superfamily, determined to 1.35 angstrom resolution, shows it to be a channel that spans the membrane 11 times. Two structurally similar halves span the membrane with opposite polarity. Structures with and without ammonia or methyl ammonia show a vestibule that recruits NH4+/NH3, a binding site for NH4+, and a 20 angstrom-long hydrophobic channel that lowers the NH4+ pKa to below 6 and conducts NH3. Favorable interactions for NH3 are seen within the channel and use conserved histidines. Reconstitution of AmtB into vesicles shows that AmtB conducts uncharged NH3.
The line below this paragraph, {{ABSTRACT_PUBMED_15361618}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 15361618 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_15361618}}


==About this Structure==
==About this Structure==
Line 33: Line 37:
[[Category: Right handed helical bundle]]
[[Category: Right handed helical bundle]]
[[Category: Transmembrane helice]]
[[Category: Transmembrane helice]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 10:50:54 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:14:39 2008''

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA