1yt9: Difference between revisions

Revision as of 13:08, 29 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:1yt9.png

Template:STRUCTURE 1yt9

HIV Protease with oximinoarylsulfonamide boundHIV Protease with oximinoarylsulfonamide bound

Template:ABSTRACT PUBMED 15837308

About this StructureAbout this Structure

1YT9 is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

ReferenceReference

Oximinoarylsulfonamides as potent HIV protease inhibitors., Yeung CM, Klein LL, Flentge CA, Randolph JT, Zhao C, Sun M, Dekhtyar T, Stoll VS, Kempf DJ, Bioorg Med Chem Lett. 2005 May 2;15(9):2275-8. PMID:15837308

Page seeded by OCA on Tue Jul 29 13:08:12 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1yt9.jpg|left|200px]]
+{{Seed}}
+[[Image:1yt9.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_1yt9|  PDB=1yt9  |  SCENE=  }}
-'''HIV Protease with oximinoarylsulfonamide bound'''
+===HIV Protease with oximinoarylsulfonamide bound===
-==Overview==
+<!--
-The need for a potent HIV protease inhibitor (PI) to combat emerging PI-resistant viruses is anticipated. Analogs formulated from the combination of structural fragments of Ritonavir, Lopinavir, and Amprenavir were synthesized. Analogs containing the oxime pharmacophore were found to have improved activities against both wild type and resistant (A17) viruses. The synthesis and structure-activity relationships (SAR) based upon the in vitro IC50 of this series of compounds are reported.
+The line below this paragraph, {{ABSTRACT_PUBMED_15837308}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 15837308 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_15837308}}
 ==About this Structure==
@@ Line 33: / Line 37: @@
 [[Category: Hiv protease]]
 [[Category: Oximinoarylsulfonamide]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 16:45:37 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:08:12 2008''