2nvt: Difference between revisions

Revision as of 09:44, 29 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:2nvt.png

Template:STRUCTURE 2nvt

RNA Polymerase II Elongation Complex in 150 mM Mg+2 with GMPCPPRNA Polymerase II Elongation Complex in 150 mM Mg+2 with GMPCPP

Template:ABSTRACT PUBMED 17129781

About this StructureAbout this Structure

2NVT is a Protein complex structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

ReferenceReference

Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis., Wang D, Bushnell DA, Westover KD, Kaplan CD, Kornberg RD, Cell. 2006 Dec 1;127(5):941-54. PMID:17129781

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OCA

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-'''RNA Polymerase II Elongation Complex in 150 mM Mg+2 with GMPCPP'''
+===RNA Polymerase II Elongation Complex in 150 mM Mg+2 with GMPCPP===
-==Overview==
+<!--
-New structures of RNA polymerase II (pol II) transcribing complexes reveal a likely key to transcription. The trigger loop swings beneath a correct nucleoside triphosphate (NTP) in the nucleotide addition site, closing off the active center and forming an extensive network of interactions with the NTP base, sugar, phosphates, and additional pol II residues. A histidine side chain in the trigger loop, precisely positioned by these interactions, may literally "trigger" phosphodiester bond formation. Recognition and catalysis are thus coupled, ensuring the fidelity of transcription.
+The line below this paragraph, {{ABSTRACT_PUBMED_17129781}}, adds the Publication Abstract to the page
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+{{ABSTRACT_PUBMED_17129781}}
 ==About this Structure==
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 [[Category: Multiprotein complex]]
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