1raz: Difference between revisions

Revision as of 08:34, 29 July 2008

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File:1raz.png

Template:STRUCTURE 1raz

THE STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH BROMIDE AND AZIDETHE STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH BROMIDE AND AZIDE

Template:ABSTRACT PUBMED 8482389

About this StructureAbout this Structure

1RAZ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

The structure of human carbonic anhydrase II in complex with bromide and azide., Jonsson BM, Hakansson K, Liljas A, FEBS Lett. 1993 May 10;322(2):186-90. PMID:8482389

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-'''THE STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH BROMIDE AND AZIDE'''
+===THE STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH BROMIDE AND AZIDE===
-==Overview==
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-The three-dimensional structure of human carbonic anhydrase II complexed with azide and with bromide was investigated crystallographically. Both of these non-protonated inhibitors replace the zinc and the 'deep' water, two catalytically important water molecules in the active site of the molecule. Both the azide and the bromide ions bind in a distorted tetrahedral manner 0.4 and 1.1 A from the zinc water position, respectively, but are in close contact (2.0 and 2.6 A, respectively) with the zinc ion.
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 [[Category: Jonsson, B M.]]
 [[Category: Liljas, A.]]
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