2yu9: Difference between revisions

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{{STRUCTURE_2yu9|  PDB=2yu9  |  SCENE=  }}  
{{STRUCTURE_2yu9|  PDB=2yu9  |  SCENE=  }}  


'''RNA polymerase II elongation complex in 150 mm MG+2 with UTP'''
===RNA polymerase II elongation complex in 150 mm MG+2 with UTP===




==Overview==
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New structures of RNA polymerase II (pol II) transcribing complexes reveal a likely key to transcription. The trigger loop swings beneath a correct nucleoside triphosphate (NTP) in the nucleotide addition site, closing off the active center and forming an extensive network of interactions with the NTP base, sugar, phosphates, and additional pol II residues. A histidine side chain in the trigger loop, precisely positioned by these interactions, may literally "trigger" phosphodiester bond formation. Recognition and catalysis are thus coupled, ensuring the fidelity of transcription.
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{{ABSTRACT_PUBMED_17129781}}


==About this Structure==
==About this Structure==
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[[Category: Multiprotein complex]]
[[Category: Multiprotein complex]]
[[Category: Transcription]]
[[Category: Transcription]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 19:27:20 2008''
 
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