1r55: Difference between revisions

Revision as of 06:49, 29 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:1r55.png

Template:STRUCTURE 1r55

Crystal structure of the catalytic domain of human ADAM 33Crystal structure of the catalytic domain of human ADAM 33

Template:ABSTRACT PUBMED 14659745

About this StructureAbout this Structure

1R55 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Crystal structure of the catalytic domain of human ADAM33., Orth P, Reichert P, Wang W, Prosise WW, Yarosh-Tomaine T, Hammond G, Ingram RN, Xiao L, Mirza UA, Zou J, Strickland C, Taremi SS, Le HV, Madison V, J Mol Biol. 2004 Jan 2;335(1):129-37. PMID:14659745

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Crystal structure of the catalytic domain of human ADAM 33'''
+===Crystal structure of the catalytic domain of human ADAM 33===
-==Overview==
+<!--
-Adam33 is a putative asthma susceptibility gene encoding for a membrane-anchored metalloprotease belonging to the ADAM family. The ADAMs (a disintegrin and metalloprotease) are a family of glycoproteins implicated in cell-cell interactions, cell fusion, and cell signaling. We have determined the crystal structure of the Adam33 catalytic domain in complex with the inhibitor marimastat and the inhibitor-free form. The structures reveal the polypeptide fold and active site environment resembling that of other metalloproteases. The substrate-binding site contains unique features that allow the structure-based design of specific inhibitors of this enzyme.
+The line below this paragraph, {{ABSTRACT_PUBMED_14659745}}, adds the Publication Abstract to the page
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+{{ABSTRACT_PUBMED_14659745}}
 ==About this Structure==
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 [[Category: Inhibitor]]
 [[Category: Metalloprotease]]
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