2jqr: Difference between revisions

Revision as of 06:37, 29 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:2jqr.png

Template:STRUCTURE 2jqr

Solution model of crosslinked complex of cytochrome c and adrenodoxinSolution model of crosslinked complex of cytochrome c and adrenodoxin

Template:ABSTRACT PUBMED 18439013

About this StructureAbout this Structure

2JQR is a Protein complex structure of sequences from Bos taurus and Saccharomyces cerevisiae. Full experimental information is available from OCA.

ReferenceReference

Dynamics in a pure encounter complex of two proteins studied by solution scattering and paramagnetic NMR spectroscopy., Xu X, Reinle W, Hannemann F, Konarev PV, Svergun DI, Bernhardt R, Ubbink M, J Am Chem Soc. 2008 May 21;130(20):6395-403. Epub 2008 Apr 26. PMID:18439013

High-resolution refinement of yeast iso-1-cytochrome c and comparisons with other eukaryotic cytochromes c., Louie GV, Brayer GD, J Mol Biol. 1990 Jul 20;214(2):527-55. PMID:2166169

New aspects of electron transfer revealed by the crystal structure of a truncated bovine adrenodoxin, Adx(4-108)., Muller A, Muller JJ, Muller YA, Uhlmann H, Bernhardt R, Heinemann U, Structure. 1998 Mar 15;6(3):269-80. PMID:9551550

Page seeded by OCA on Tue Jul 29 06:37:06 2008

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OCA

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 {{STRUCTURE_2jqr|  PDB=2jqr  |  SCENE=  }}
-'''Solution model of crosslinked complex of cytochrome c and adrenodoxin'''
+===Solution model of crosslinked complex of cytochrome c and adrenodoxin===
-==Overview==
+<!--
-In the general view of protein-complex formation, a transient and dynamic encounter complex proceeds to form a more stable, well-defined, and active form. In weak protein complexes, however, the encounter state can represent a significant population of the complex. The redox proteins adrenodoxin (Adx) and cytochrome c (C c) associate to form such a weak and short-lived complex, which is nevertheless active in electron transfer. To study the conformational freedom within the protein complex, the native complex has been compared to a cross-linked counterpart by using solution scattering and NMR spectroscopy. Oligomerization behavior of the native complex in solution revealed by small-angle X-ray scattering indicates a stochastic nature of complex formation. For the cross-linked complex, interprotein paramagnetic effects are observed, whereas for the native complex, extensive averaging occurs, consistent with multiple orientations of the proteins within the complex. Simulations show that C c samples about half of the surface area of adrenodoxin. It is concluded that the complex of Adx/C c is entirely dynamic and can be considered as a pure encounter complex.
+The line below this paragraph, {{ABSTRACT_PUBMED_18439013}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18439013 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18439013}}
 ==About this Structure==
-JQR is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JQR OCA].
+JQR is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JQR OCA].
 ==Reference==
 Dynamics in a pure encounter complex of two proteins studied by solution scattering and paramagnetic NMR spectroscopy., Xu X, Reinle W, Hannemann F, Konarev PV, Svergun DI, Bernhardt R, Ubbink M, J Am Chem Soc. 2008 May 21;130(20):6395-403. Epub 2008 Apr 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18439013 18439013]
+High-resolution refinement of yeast iso-1-cytochrome c and comparisons with other eukaryotic cytochromes c., Louie GV, Brayer GD, J Mol Biol. 1990 Jul 20;214(2):527-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2166169 2166169]
+New aspects of electron transfer revealed by the crystal structure of a truncated bovine adrenodoxin, Adx(4-108)., Muller A, Muller JJ, Muller YA, Uhlmann H, Bernhardt R, Heinemann U, Structure. 1998 Mar 15;6(3):269-80. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9551550 9551550]
 [[Category: Bos taurus]]
 [[Category: Protein complex]]
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 [[Category: Paramagnetic relaxation enhancement]]
 [[Category: Pseudocontact shift]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 10:54:17 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 06:37:06 2008''