2qcf: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
[[Image:2qcf. | {{Seed}} | ||
[[Image:2qcf.png|left|200px]] | |||
<!-- | <!-- | ||
Line 9: | Line 10: | ||
{{STRUCTURE_2qcf| PDB=2qcf | SCENE= }} | {{STRUCTURE_2qcf| PDB=2qcf | SCENE= }} | ||
===Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP=== | |||
<!-- | |||
The line below this paragraph, {{ABSTRACT_PUBMED_18184586}}, adds the Publication Abstract to the page | |||
(as it appears on PubMed at http://www.pubmed.gov), where 18184586 is the PubMed ID number. | |||
--> | |||
{{ABSTRACT_PUBMED_18184586}} | |||
==Disease== | ==Disease== | ||
Line 32: | Line 36: | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Ump synthase]] | [[Category: Ump synthase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:02:58 2008'' |
Revision as of 05:03, 29 July 2008
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMPCrystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP
Template:ABSTRACT PUBMED 18184586
DiseaseDisease
Known disease associated with this structure: Oroticaciduria OMIM:[258900]
About this StructureAbout this Structure
2QCF is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design., Wittmann JG, Heinrich D, Gasow K, Frey A, Diederichsen U, Rudolph MG, Structure. 2008 Jan;16(1):82-92. PMID:18184586
Page seeded by OCA on Tue Jul 29 05:02:58 2008