2hth: Difference between revisions

Revision as of 04:26, 29 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:2hth.png

Template:STRUCTURE 2hth

Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domainStructural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain

Template:ABSTRACT PUBMED 17057716

About this StructureAbout this Structure

2HTH is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain., Alam SL, Langelier C, Whitby FG, Koirala S, Robinson H, Hill CP, Sundquist WI, Nat Struct Mol Biol. 2006 Nov;13(11):1029-30. Epub 2006 Oct 22. PMID:17057716

Page seeded by OCA on Tue Jul 29 04:26:00 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain'''
+===Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain===
-==Overview==
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-The ESCRT-I and ESCRT-II complexes help sort ubiquitinated proteins into vesicles that accumulate within multivesicular bodies (MVBs). Crystallographic and biochemical analyses reveal that the GLUE domain of the human ESCRT-II EAP45 (also called VPS36) subunit is a split pleckstrin-homology domain that binds ubiquitin along one edge of the beta-sandwich. The structure suggests how human ESCRT-II can couple recognition of ubiquitinated cargoes and endosomal phospholipids during MVB protein sorting.
+The line below this paragraph, {{ABSTRACT_PUBMED_17057716}}, adds the Publication Abstract to the page
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+{{ABSTRACT_PUBMED_17057716}}
 ==About this Structure==
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 [[Category: Ubiquitin complex]]
 [[Category: Viral budding]]
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