2fp7: Difference between revisions

Revision as of 03:46, 29 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:2fp7.png

Template:STRUCTURE 2fp7

West Nile Virus NS2B/NS3protease in complex with Bz-Nle-Lys-Arg-Arg-HWest Nile Virus NS2B/NS3protease in complex with Bz-Nle-Lys-Arg-Arg-H

Template:ABSTRACT PUBMED 16532006

About this StructureAbout this Structure

2FP7 is a Protein complex structure of sequences from West nile virus. Full crystallographic information is available from OCA.

ReferenceReference

Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus., Erbel P, Schiering N, D'Arcy A, Renatus M, Kroemer M, Lim SP, Yin Z, Keller TH, Vasudevan SG, Hommel U, Nat Struct Mol Biol. 2006 Apr;13(4):372-3. Epub 2006 Mar 12. PMID:16532006

Page seeded by OCA on Tue Jul 29 03:46:01 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:2fp7.gif|left|200px]]
+{{Seed}}
+[[Image:2fp7.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_2fp7|  PDB=2fp7  |  SCENE=  }}
-'''West Nile Virus NS2B/NS3protease in complex with Bz-Nle-Lys-Arg-Arg-H'''
+===West Nile Virus NS2B/NS3protease in complex with Bz-Nle-Lys-Arg-Arg-H===
-==Overview==
+<!--
-The replication of flaviviruses requires the correct processing of their polyprotein by the viral NS3 protease (NS3pro). Essential for the activation of NS3pro is a 47-residue region of NS2B. Here we report the crystal structures of a dengue NS2B-NS3pro complex and a West Nile virus NS2B-NS3pro complex with a substrate-based inhibitor. These structures identify key residues for NS3pro substrate recognition and clarify the mechanism of NS3pro activation.
+The line below this paragraph, {{ABSTRACT_PUBMED_16532006}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 16532006 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_16532006}}
 ==About this Structure==
@@ Line 30: / Line 34: @@
 [[Category: Ns3 protease]]
 [[Category: Substrate-based inhibitor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 04:09:43 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:46:01 2008''