2ajl: Difference between revisions

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[[Image:2ajl.gif|left|200px]]
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{{STRUCTURE_2ajl|  PDB=2ajl  |  SCENE=  }}  
{{STRUCTURE_2ajl|  PDB=2ajl  |  SCENE=  }}  


'''X-ray Structure of Novel Biaryl-Based Dipeptidyl peptidase IV inhibitor'''
===X-ray Structure of Novel Biaryl-Based Dipeptidyl peptidase IV inhibitor===




==Overview==
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The discovery, SAR, and X-ray crystal structure of novel biarylaminoacyl-(S)-2-cyano-pyrrolidines and biarylaminoacylthiazolidines as potent inhibitors of dipeptidyl peptidase IV (DPP IV) are reported.
The line below this paragraph, {{ABSTRACT_PUBMED_16236500}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_16236500}}


==About this Structure==
==About this Structure==
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[[Category: Protease]]
[[Category: Protease]]
[[Category: Serine protease]]
[[Category: Serine protease]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 19:07:58 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 21:37:36 2008''

Revision as of 21:37, 28 July 2008

File:2ajl.png

Template:STRUCTURE 2ajl

X-ray Structure of Novel Biaryl-Based Dipeptidyl peptidase IV inhibitorX-ray Structure of Novel Biaryl-Based Dipeptidyl peptidase IV inhibitor

Template:ABSTRACT PUBMED 16236500

About this StructureAbout this Structure

2AJL is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors., Qiao L, Baumann CA, Crysler CS, Ninan NS, Abad MC, Spurlino JC, Desjarlais RL, Kervinen J, Neeper MP, Bayoumy SS, Williams R, Deckman IC, Dasgupta M, Reed RL, Huebert ND, Tomczuk BE, Moriarty KJ, Bioorg Med Chem Lett. 2006 Jan 1;16(1):123-8. Epub 2005 Oct 19. PMID:16236500

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