2uy0: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-[[Image:2uy0.jpg|left|200px]]
+{{Seed}}
+[[Image:2uy0.png|left|200px]]
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 {{STRUCTURE_2uy0|  PDB=2uy0  |  SCENE=  }}
-'''TWO-CARBON-ELONGATED HIV-1 PROTEASE INHIBITORS WITH A TERTIARY-ALCOHOL-CONTAINING TRANSITION-STATE MIMIC'''
+===TWO-CARBON-ELONGATED HIV-1 PROTEASE INHIBITORS WITH A TERTIARY-ALCOHOL-CONTAINING TRANSITION-STATE MIMIC===
-==Overview==
+<!--
-A new generation of HIV-1 protease inhibitors encompassing a tertiary-alcohol-based transition-state mimic has been developed. By elongation of the core structure of recently reported inhibitors with two carbon atoms and by varying the P1' group of the compounds, efficient inhibitors were obtained with Ki down to 2.3 nM and EC50 down to 0.17 microM. Two inhibitor-enzyme X-ray structures are reported.
+The line below this paragraph, {{ABSTRACT_PUBMED_18215014}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18215014 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18215014}}
 ==About this Structure==
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 [[Category: Inhibitor]]
 [[Category: Protease]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 22 21:38:09 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:21:18 2008''