1r5e: Difference between revisions

Revision as of 18:55, 28 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:1r5e.png

Template:STRUCTURE 1r5e

Solution structure of the folded core of Pseudomonas syringae effector protein, AvrPtoSolution structure of the folded core of Pseudomonas syringae effector protein, AvrPto

Template:ABSTRACT PUBMED 15242602

About this StructureAbout this Structure

1R5E is a Single protein structure of sequence from Pseudomonas syringae. Full experimental information is available from OCA.

ReferenceReference

The solution structure of type III effector protein AvrPto reveals conformational and dynamic features important for plant pathogenesis., Wulf J, Pascuzzi PE, Fahmy A, Martin GB, Nicholson LK, Structure. 2004 Jul;12(7):1257-68. PMID:15242602

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 {{STRUCTURE_1r5e|  PDB=1r5e  |  SCENE=  }}
-'''Solution structure of the folded core of Pseudomonas syringae effector protein, AvrPto'''
+===Solution structure of the folded core of Pseudomonas syringae effector protein, AvrPto===
-==Overview==
+<!--
-Pseudomonas syringae pv. tomato, the causative agent of bacterial speck disease of tomato, uses a type III secretion system (TTSS) to deliver effector proteins into the host cell. In resistant plants, the bacterial effector protein AvrPto physically interacts with the host Pto kinase and elicits antibacterial defense responses. In susceptible plants, which lack the Pto kinase, AvrPto acts as a virulence factor to promote bacterial growth. The solution structure of AvrPto reveals a functional core consisting of a three-helix bundle motif flanked by disordered N- and C-terminal tails. Residues required for Pto binding lie in a 19 residue Omega loop. Modeling suggests a hydrophobic patch involving the activation loop of Pto forms a contact surface with the AvrPto Omega loop and that helix packing mediates interactions between AvrPto and putative virulence targets Api2 and Api3. The AvrPto structure has a low stability that may facilitate chaperone-independent secretion by the TTSS.
+The line below this paragraph, {{ABSTRACT_PUBMED_15242602}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 15242602 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_15242602}}
 ==About this Structure==
-R5E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae Pseudomonas syringae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R5E OCA].
+R5E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae Pseudomonas syringae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R5E OCA].
 ==Reference==
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 [[Category: Omega loop]]
 [[Category: Three-helix bundle]]
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