2ewp: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

@@ Line 1: / Line 1: @@
-[[Image:2ewp.gif|left|200px]]
+{{Seed}}
+[[Image:2ewp.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_2ewp|  PDB=2ewp  |  SCENE=  }}
-'''Crystal structure of Estrogen Related Reecptor-3 (ERR-gamma) ligand binding domaind with tamoxifen analog GSK5182'''
+===Crystal structure of Estrogen Related Reecptor-3 (ERR-gamma) ligand binding domaind with tamoxifen analog GSK5182===
-==Overview==
+<!--
-The design and synthesis of 4-hydroxytamoxifen (4-OHT) derivatives are described. The binding affinities of these compounds toward the orphan estrogen-related receptor gamma and the classical estrogen receptor alpha demonstrate that analogs bearing hydroxyalkyl groups display improved binding selectivity profiles compared with that of 4-OHT. An X-ray crystal structure of one of the designed compounds bound to ERRgamma LBD confirms the molecular basis of the selectivity.
+The line below this paragraph, {{ABSTRACT_PUBMED_16307879}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 16307879 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_16307879}}
 ==About this Structure==
@@ Line 27: / Line 31: @@
 [[Category: Orphan receptor]]
 [[Category: Tamoxifen]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 03:12:03 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 14:25:41 2008''