2g7h: Difference between revisions

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{{STRUCTURE_2g7h|  PDB=2g7h  |  SCENE=  }}  
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'''Structure of an O6-Methylguanine DNA Methyltransferase from Methanococcus jannaschii (MJ1529)'''
===Structure of an O6-Methylguanine DNA Methyltransferase from Methanococcus jannaschii (MJ1529)===




==Overview==
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The structure of an O6-methylguanine-DNA methyltransferase (MGMT) from the thermophile Methanococcus jannaschii has been determined using multinuclear multidimensional NMR spectroscopy. The structure is similar to homologs from other organisms that have been determined by crystallography, with some variation in the N-terminal domain. The C-terminal domain is more highly conserved in both sequence and structure. Regions of the protein show broadening, reflecting conformational flexibility that is likely related to function.
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{{ABSTRACT_PUBMED_16826543}}


==About this Structure==
==About this Structure==
2G7H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G7H OCA].  
2G7H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G7H OCA].  


==Reference==
==Reference==
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[[Category: Nmr]]
[[Category: Nmr]]
[[Category: Protein structure]]
[[Category: Protein structure]]
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Revision as of 13:50, 28 July 2008

File:2g7h.png

Template:STRUCTURE 2g7h

Structure of an O6-Methylguanine DNA Methyltransferase from Methanococcus jannaschii (MJ1529)Structure of an O6-Methylguanine DNA Methyltransferase from Methanococcus jannaschii (MJ1529)

Template:ABSTRACT PUBMED 16826543

About this StructureAbout this Structure

2G7H is a Single protein structure of sequence from Methanocaldococcus jannaschii. Full experimental information is available from OCA.

ReferenceReference

Structural studies of MJ1529, an O6-methylguanine-DNA methyltransferase., Roberts A, Pelton JG, Wemmer DE, Magn Reson Chem. 2006 Jul;44 Spec No:S71-82. PMID:16826543

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