1rio: Difference between revisions

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-[[Image:1rio.gif|left|200px]]
+{{Seed}}
+[[Image:1rio.png|left|200px]]
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 {{STRUCTURE_1rio|  PDB=1rio  |  SCENE=  }}
-'''Structure of bacteriophage lambda cI-NTD in complex with sigma-region4 of Thermus aquaticus bound to DNA'''
+===Structure of bacteriophage lambda cI-NTD in complex with sigma-region4 of Thermus aquaticus bound to DNA===
-==Overview==
+<!--
-The cI protein of bacteriophage lambda (lambdacI) activates transcription by binding a DNA operator just upstream of the promoter and interacting with the RNA polymerase sigma subunit domain 4 (sigma(4)). We determined the crystal structure of the lambdacI/sigma(4)/DNA ternary complex at 2.3 A resolution. There are no conformational changes in either protein, which interact through an extremely small interface involving at most 6 amino acid residues. The interactions of the two proteins stabilize the binding of each protein to the DNA. The results provide insight into how activators can operate through a simple cooperative binding mechanism but affect different steps of the transcription initiation process.
+The line below this paragraph, {{ABSTRACT_PUBMED_14731393}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 14731393 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_14731393}}
 ==About this Structure==
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 [[Category: Helix-turn-helix]]
 [[Category: Transcription activation]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 07:32:44 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 10:17:50 2008''