2j4i: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-[[Image:2j4i.jpg|left|200px]]
+{{Seed}}
+[[Image:2j4i.png|left|200px]]
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 {{STRUCTURE_2j4i|  PDB=2j4i  |  SCENE=  }}
-'''CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX'''
+===CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX===
-==Overview==
+<!--
-Structure-based drug design was exploited in the synthesis of 3-(6-chloronaphth-2-ylsulfonyl)aminopyrrolidin-2-one-based factor Xa (fXa) inhibitors, incorporating an alanylamide P4 group with acyclic tertiary amide termini. Optimized hydrophobic contacts of one amide substituent in P4 were complemented by hydrophobicity-modulating features in the second, producing potent fXa inhibitors including examples with excellent anticoagulant properties.
+The line below this paragraph, {{ABSTRACT_PUBMED_16982190}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 16982190 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_16982190}}
 ==About this Structure==
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 [[Category: Serine protease]]
 [[Category: Zymogen]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 08:19:18 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 10:15:15 2008''