1q3f: Difference between revisions

Revision as of 08:04, 28 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:1q3f.png

Template:STRUCTURE 1q3f

Uracil DNA glycosylase bound to a cationic 1-aza-2'-deoxyribose-contianing DNAUracil DNA glycosylase bound to a cationic 1-aza-2'-deoxyribose-contianing DNA

Template:ABSTRACT PUBMED 14580190

About this StructureAbout this Structure

1Q3F is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Electrostatic guidance of glycosyl cation migration along the reaction coordinate of uracil DNA glycosylase., Bianchet MA, Seiple LA, Jiang YL, Ichikawa Y, Amzel LM, Stivers JT, Biochemistry. 2003 Nov 4;42(43):12455-60. PMID:14580190

Page seeded by OCA on Mon Jul 28 08:04:27 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:1q3f.gif|left|200px]]
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 {{STRUCTURE_1q3f|  PDB=1q3f  |  SCENE=  }}
-'''Uracil DNA glycosylase bound to a cationic 1-aza-2'-deoxyribose-contianing DNA'''
+===Uracil DNA glycosylase bound to a cationic 1-aza-2'-deoxyribose-contianing DNA===
-==Overview==
+<!--
-The DNA repair enzyme uracil DNA glycosylase has been crystallized with a cationic 1-aza-2'-deoxyribose-containing DNA that mimics the ultimate transition state of the reaction in which the water nucleophile attacks the anomeric center of the oxacarbenium ion-uracil anion reaction intermediate. Comparison with substrate and product structures, and the previous structure of the intermediate determined by kinetic isotope effects, reveals an exquisite example of geometric strain, least atomic motion, and electrophile migration in biological catalysis. This structure provides a rare opportunity to reconstruct the detailed structural transformations that occur along an enzymatic reaction coordinate.
+The line below this paragraph, {{ABSTRACT_PUBMED_14580190}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 14580190 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_14580190}}
 ==About this Structure==
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 [[Category: Dna repair]]
 [[Category: Udg]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 05:49:10 2008''
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