2zb1: Difference between revisions

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{{STRUCTURE_2zb1|  PDB=2zb1  |  SCENE=  }}  
{{STRUCTURE_2zb1|  PDB=2zb1  |  SCENE=  }}  


'''Crystal structure of P38 in complex with biphenyl amide inhibitor'''
===Crystal structure of P38 in complex with biphenyl amide inhibitor===




==Overview==
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The biphenyl amides (BPAs) are a novel series of p38 MAP kinase inhibitors. The discovery of the series through structure-based focused screening is described, and the binding mode of the compounds is explained with reference to X-ray crystal structures.
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{{ABSTRACT_PUBMED_18006306}}


==About this Structure==
==About this Structure==
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[[Category: Serine/threonine protein kinase]]
[[Category: Serine/threonine protein kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 20:06:20 2008''
 
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Revision as of 07:26, 28 July 2008

File:2zb1.png

Template:STRUCTURE 2zb1

Crystal structure of P38 in complex with biphenyl amide inhibitorCrystal structure of P38 in complex with biphenyl amide inhibitor

Template:ABSTRACT PUBMED 18006306

About this StructureAbout this Structure

2ZB1 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode., Angell RM, Bamborough P, Cleasby A, Cockerill SG, Jones KL, Mooney CJ, Somers DO, Walker AL, Bioorg Med Chem Lett. 2008 Jan 1;18(1):318-23. Epub 2007 Nov 19. PMID:18006306

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