2by6: Difference between revisions

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[[Image:2by6.gif|left|200px]]
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{{STRUCTURE_2by6|  PDB=2by6  |  SCENE=  }}  
{{STRUCTURE_2by6|  PDB=2by6  |  SCENE=  }}  


'''IS RADIATION DAMAGE DEPENDENT ON THE DOSE-RATE USED DURING MACROMOLECULAR CRYSTALLOGRAPHY DATA COLLECTION'''
===IS RADIATION DAMAGE DEPENDENT ON THE DOSE-RATE USED DURING MACROMOLECULAR CRYSTALLOGRAPHY DATA COLLECTION===




==Overview==
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This paper focuses on the radiation-damage effects when applying the same total X-ray dose to protein crystals at different dose rates. These experiments have been performed on both a selenomethionated protein and on bovine trypsin using dose rates that span nearly two orders of magnitude. The results show no clear dose-rate effect on the global indicators of radiation damage, but a small measurable dose-rate effect could be found when studying specific radiation damage. It is hypothesized that this observed dose-rate effect relates to differences in the steady-state free-radical concentration.
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==About this Structure==
==About this Structure==
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[[Category: Timmins, J.]]
[[Category: Timmins, J.]]
[[Category: Data collection,radiation damage,dose-rate,synchrotron radiation,hydrolase]]
[[Category: Data collection,radiation damage,dose-rate,synchrotron radiation,hydrolase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 20:57:30 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 07:01:57 2008''

Revision as of 07:01, 28 July 2008

File:2by6.png

Template:STRUCTURE 2by6

IS RADIATION DAMAGE DEPENDENT ON THE DOSE-RATE USED DURING MACROMOLECULAR CRYSTALLOGRAPHY DATA COLLECTIONIS RADIATION DAMAGE DEPENDENT ON THE DOSE-RATE USED DURING MACROMOLECULAR CRYSTALLOGRAPHY DATA COLLECTION

Template:ABSTRACT PUBMED 16421442

About this StructureAbout this Structure

2BY6 is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

ReferenceReference

Is radiation damage dependent on the dose rate used during macromolecular crystallography data collection?, Leiros HK, Timmins J, Ravelli RB, McSweeney SM, Acta Crystallogr D Biol Crystallogr. 2006 Feb;62(Pt 2):125-32. Epub 2006, Jan 18. PMID:16421442

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