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-[[Image:1par.gif|left|200px]]
+{{Seed}}
+[[Image:1par.png|left|200px]]
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 {{STRUCTURE_1par|  PDB=1par  |  SCENE=  }}
-'''DNA RECOGNITION BY BETA-SHEETS IN THE ARC REPRESSOR-OPERATOR CRYSTAL STRUCTURE'''
+===DNA RECOGNITION BY BETA-SHEETS IN THE ARC REPRESSOR-OPERATOR CRYSTAL STRUCTURE===
-==Overview==
+<!--
-Transcription of the ant gene during lytic growth of bacteriophage P22 (ref. 1) is regulated by the cooperative binding of two Arc repressor dimers to a 21-base-pair operator site. Here we report the co-crystal structure of this Arc tetramer-operator complex at 2.6 A resolution. As expected from genetic and structural studies and from the co-crystal structure of the homologous Escherichia coli MetJ repressor, each Arc dimer uses an antiparallel beta-sheet to recognize bases in the major groove. However, the Arc and MetJ complexes differ in several important ways: the beta-sheet-DNA interactions of Arc are far less symmetrical; DNA binding by Arc is accompanied by important conformational changes in the beta-sheet; and Arc uses a different part of its protein surface for dimer-dimer interactions.
+The line below this paragraph, {{ABSTRACT_PUBMED_8107872}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 8107872 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_8107872}}
 ==About this Structure==
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 [[Category: Double helix]]
 [[Category: Protein-dna complex]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 04:53:24 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:17:57 2008''