2hrt: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:2hrt.jpg|left|200px]]
+{{Seed}}
+[[Image:2hrt.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_2hrt|  PDB=2hrt  |  SCENE=  }}
-'''Asymmetric structure of trimeric AcrB from Escherichia coli'''
+===Asymmetric structure of trimeric AcrB from Escherichia coli===
-==Overview==
+<!--
-The AcrA/AcrB/TolC complex spans the inner and outer membranes of Escherichia coli and serves as its major drug-resistance pump. Driven by the proton motive force, it mediates the efflux of bile salts, detergents, organic solvents, and many structurally unrelated antibiotics. Here, we report a crystallographic structure of trimeric AcrB determined at 2.9 and 3.0 angstrom resolution in space groups that allow asymmetry of the monomers. This structure reveals three different monomer conformations representing consecutive states in a transport cycle. The structural data imply an alternating access mechanism and a novel peristaltic mode of drug transport by this type of transporter.
+The line below this paragraph, {{ABSTRACT_PUBMED_16946072}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 16946072 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_16946072}}
 ==About this Structure==
@@ Line 36: / Line 40: @@
 [[Category: Rnd]]
 [[Category: Tolc]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 06:38:15 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 04:51:12 2008''