2bjw: Difference between revisions

Revision as of 04:14, 28 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:2bjw.png

Template:STRUCTURE 2bjw

PSPF AAA DOMAINPSPF AAA DOMAIN

Template:ABSTRACT PUBMED 15790859

About this StructureAbout this Structure

2BJW is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

ReferenceReference

Structural insights into the activity of enhancer-binding proteins., Rappas M, Schumacher J, Beuron F, Niwa H, Bordes P, Wigneshweraraj S, Keetch CA, Robinson CV, Buck M, Zhang X, Science. 2005 Mar 25;307(5717):1972-5. PMID:15790859

Page seeded by OCA on Mon Jul 28 04:14:26 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''PSPF AAA DOMAIN'''
+===PSPF AAA DOMAIN===
-==Overview==
+<!--
-Activators of bacterial sigma54-RNA polymerase holoenzyme are mechanochemical proteins that use adenosine triphosphate (ATP) hydrolysis to activate transcription. We have determined by cryogenic electron microscopy (cryo-EM) a 20 angstrom resolution structure of an activator, phage shock protein F [PspF(1-275)], which is bound to an ATP transition state analog in complex with its basal factor, sigma54. By fitting the crystal structure of PspF(1-275) at 1.75 angstroms into the EM map, we identified two loops involved in binding sigma54. Comparing enhancer-binding structures in different nucleotide states and mutational analysis led us to propose nucleotide-dependent conformational changes that free the loops for association with sigma54.
+The line below this paragraph, {{ABSTRACT_PUBMED_15790859}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 15790859 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_15790859}}
 ==About this Structure==
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 [[Category: Sigma54 activator]]
 [[Category: Transcription regulation]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 20:23:27 2008''
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