2fji: Difference between revisions

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[[Image:2fji.gif|left|200px]]
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{{STRUCTURE_2fji|  PDB=2fji  |  SCENE=  }}  
{{STRUCTURE_2fji|  PDB=2fji  |  SCENE=  }}  


'''Crystal structure of the C-terminal domain of the exocyst subunit Sec6p'''
===Crystal structure of the C-terminal domain of the exocyst subunit Sec6p===




==Overview==
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The exocyst is a conserved protein complex essential for trafficking secretory vesicles to the plasma membrane. The structure of the C-terminal domain of the exocyst subunit Sec6p reveals multiple helical bundles, which are structurally and topologically similar to Exo70p and the C-terminal domains of Exo84p and Sec15, despite &lt;10% sequence identity. The helical bundles appear to be evolutionarily related molecular scaffolds that have diverged to create functionally distinct exocyst proteins.
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{{ABSTRACT_PUBMED_16699513}}


==About this Structure==
==About this Structure==
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[[Category: Exocytosis]]
[[Category: Exocytosis]]
[[Category: Tandem helical bundle]]
[[Category: Tandem helical bundle]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 03:58:20 2008''
 
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Revision as of 03:07, 28 July 2008

File:2fji.png

Template:STRUCTURE 2fji

Crystal structure of the C-terminal domain of the exocyst subunit Sec6pCrystal structure of the C-terminal domain of the exocyst subunit Sec6p

Template:ABSTRACT PUBMED 16699513

About this StructureAbout this Structure

2FJI is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

ReferenceReference

The structure of the exocyst subunit Sec6p defines a conserved architecture with diverse roles., Sivaram MV, Furgason ML, Brewer DN, Munson M, Nat Struct Mol Biol. 2006 Jun;13(6):555-6. Epub 2006 May 14. PMID:16699513

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