2pxu: Difference between revisions

Revision as of 22:54, 27 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:2pxu.png

Template:STRUCTURE 2pxu

Variant 16 of Ribonucleoprotein Core of the E. Coli Signal Recognition ParticleVariant 16 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle

Template:ABSTRACT PUBMED 17637337

About this StructureAbout this Structure

2PXU is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

ReferenceReference

A general strategy to solve the phase problem in RNA crystallography., Keel AY, Rambo RP, Batey RT, Kieft JS, Structure. 2007 Jul;15(7):761-72. PMID:17637337

Page seeded by OCA on Sun Jul 27 22:54:07 2008

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OCA

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-[[Image:2pxu.gif|left|200px]]
+{{Seed}}
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 {{STRUCTURE_2pxu|  PDB=2pxu  |  SCENE=  }}
-'''Variant 16 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle'''
+===Variant 16 of Ribonucleoprotein Core of the E. Coli Signal Recognition Particle===
-==Overview==
+<!--
-X-ray crystallography of biologically important RNA molecules has been hampered by technical challenges, including finding heavy-atom derivatives to obtain high-quality experimental phase information. Existing techniques have drawbacks, limiting the rate at which important new structures are solved. To address this, we have developed a reliable means to localize heavy atoms specifically to virtually any RNA. By solving the crystal structures of thirteen variants of the G*U wobble pair cation binding motif, we have identified a version that when inserted into an RNA helix introduces a high-occupancy cation binding site suitable for phasing. This "directed soaking" strategy can be integrated fully into existing RNA crystallography methods, potentially increasing the rate at which important structures are solved and facilitating routine solving of structures using Cu-Kalpha radiation. This method already has been used to solve several crystal structures.
+The line below this paragraph, {{ABSTRACT_PUBMED_17637337}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 17637337 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_17637337}}
 ==About this Structure==
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 [[Category: Rna phasing]]
 [[Category: Signaling protein/rna complex]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 13:59:26 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 22:54:07 2008''