1xuo: Difference between revisions

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{{STRUCTURE_1xuo|  PDB=1xuo  |  SCENE=  }}  
{{STRUCTURE_1xuo|  PDB=1xuo  |  SCENE=  }}  


'''X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution'''
===X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution===




==Overview==
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1,4-Diazepane-2,5-diones (2) are found to be a new class of potent LFA-1 inhibitors. The synthesis, structure, and biological evaluation of these 1,4-diazepine-2,5-diones and related derivatives are described.
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{{ABSTRACT_PUBMED_15686945}}


==About this Structure==
==About this Structure==
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[[Category: I-domain]]
[[Category: I-domain]]
[[Category: Integrin]]
[[Category: Integrin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 15:31:52 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:23:53 2008''

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