1nt1: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-[[Image:1nt1.jpg|left|200px]]
+{{Seed}}
+[[Image:1nt1.png|left|200px]]
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 {{STRUCTURE_1nt1|  PDB=1nt1  |  SCENE=  }}
-'''thrombin in complex with selective macrocyclic inhibitor'''
+===thrombin in complex with selective macrocyclic inhibitor===
-==Overview==
+<!--
-A series of potent and selective proline- and pyrazinone-based macrocyclic thrombin inhibitors is described. Detailed SAR studies led to the incorporation of specific functional groups in the tether that enhanced functional activity against thrombin and provided exquisite selectivity against trypsin and tPA. X-ray crystallography and molecular modeling studies revealed the inhibitor-enzyme interactions responsible for this selectivity.
+The line below this paragraph, {{ABSTRACT_PUBMED_12873514}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 12873514 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_12873514}}
 ==About this Structure==
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 [[Category: Young, M.]]
 [[Category: Thrombin inhibitor complex]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 02:56:37 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 18:58:38 2008''