2jqt: Difference between revisions

Revision as of 16:33, 27 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:2jqt.png

Template:STRUCTURE 2jqt

Structure of the bacterial replication origin-associated protein CnuStructure of the bacterial replication origin-associated protein Cnu

Template:ABSTRACT PUBMED 18189420

About this StructureAbout this Structure

2JQT is a Single protein structure of sequence from Escherichia coli. Full experimental information is available from OCA.

ReferenceReference

Structure of the nucleoid-associated protein Cnu reveals common binding sites for H-NS in Cnu and Hha., Bae SH, Liu D, Lim HM, Lee Y, Choi BS, Biochemistry. 2008 Feb 19;47(7):1993-2001. Epub 2008 Jan 12. PMID:18189420

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Structure of the bacterial replication origin-associated protein Cnu'''
+===Structure of the bacterial replication origin-associated protein Cnu===
-==Overview==
+<!--
-Cnu is a nucleoid protein that has a high degree of sequence homology with Hha/YmoA family proteins, which bind to chromatin and regulate the expression of Escherichia coli virulence genes in response to changes in temperature or ionic strength. Here, we determined its solution structure and dynamic properties and mapped H-NS binding sites. Cnu consists of three alpha helices that are comparable with those of Hha, but it has significant flexibility in the C-terminal region and lacks a short alpha helix present in Hha. Upon increasing ionic strength, the helical structure of Cnu is destabilized, especially at the ends of the helices. The dominant H-NS binding sites, located at helix 3 as in Hha, reveal a common structural platform for H-NS binding. Our results may provide structural and dynamic bases for the similarity and dissimilarity between Cnu and Hha functions.
+The line below this paragraph, {{ABSTRACT_PUBMED_18189420}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18189420 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18189420}}
 ==About this Structure==
-JQT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JQT OCA].
+JQT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JQT OCA].
 ==Reference==
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 [[Category: Replication origin associated]]
 [[Category: Ydgt]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 24 09:37:14 2008''
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