2pkv: Difference between revisions

Revision as of 14:29, 27 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:2pkv.png

Template:STRUCTURE 2pkv

D-(GGTATACC) ambient pressureD-(GGTATACC) ambient pressure

Template:ABSTRACT PUBMED 17617642

About this StructureAbout this Structure

Full crystallographic information is available from OCA.

ReferenceReference

Adaptation of the base-paired double-helix molecular architecture to extreme pressure., Girard E, Prange T, Dhaussy AC, Migianu-Griffoni E, Lecouvey M, Chervin JC, Mezouar M, Kahn R, Fourme R, Nucleic Acids Res. 2007;35(14):4800-8. Epub 2007 Jul 7. PMID:17617642

Coexistence of A- and B-form DNA in a single crystal lattice., Doucet J, Benoit JP, Cruse WB, Prange T, Kennard O, Nature. 1989 Jan 12;337(6203):190-2. PMID:2911354

High-pressure protein crystallography (HPPX): instrumentation, methodology and results on lysozyme crystals., Fourme R, Kahn R, Mezouar M, Girard E, Hoerentrup C, Prange T, Ascone I, J Synchrotron Radiat. 2001 Sep 1;8(Pt 5):1149-56. Epub 2001 Aug 28. PMID:11524565

High pressure macromolecular crystallography: the 140-MPa crystal structure at 2.3 A resolution of urate oxidase, a 135-kDa tetrameric assembly., Colloc'h N, Girard E, Dhaussy AC, Kahn R, Ascone I, Mezouar M, Fourme R, Biochim Biophys Acta. 2006 Mar;1764(3):391-7. Epub 2006 Jan 26. PMID:16478683

Crystal structure of hen egg-white lysozyme at a hydrostatic pressure of 1000 atmospheres., Kundrot CE, Richards FM, J Mol Biol. 1987 Jan 5;193(1):157-70. PMID:3586017

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-'''D-(GGTATACC) ambient pressure'''
+===D-(GGTATACC) ambient pressure===
-==Overview==
+<!--
-The behaviour of the d(GGTATACC) oligonucleotide has been investigated by X-ray crystallography at 295 K in the range from ambient pressure to 2 GPa (approximately 20,000 atm). Four 3D-structures of the A-DNA form (at ambient pressure, 0.55, 1.09 and 1.39 GPa) were refined at 1.60 or 1.65 A resolution. In addition to the diffraction pattern of the A-form, the broad meridional streaks previously explained by occluded B-DNA octamers within the channels of the crystalline A-form matrix were observed up to at least 2 GPa. This work highlights an important property of nucleic acids, their capability to withstand very high pressures, while keeping in such conditions a nearly invariant geometry of base pairs that store and carry genetic information. The double-helix base-paired architecture behaves as a molecular spring, which makes it especially adapted to very harsh conditions. These features may have contributed to the emergence of a RNA World at prebiotic stage.
+The line below this paragraph, {{ABSTRACT_PUBMED_17617642}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 17617642 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_17617642}}
 ==About this Structure==
@@ Line 20: / Line 24: @@
 ==Reference==
 Adaptation of the base-paired double-helix molecular architecture to extreme pressure., Girard E, Prange T, Dhaussy AC, Migianu-Griffoni E, Lecouvey M, Chervin JC, Mezouar M, Kahn R, Fourme R, Nucleic Acids Res. 2007;35(14):4800-8. Epub 2007 Jul 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17617642 17617642]
+Coexistence of A- and B-form DNA in a single crystal lattice., Doucet J, Benoit JP, Cruse WB, Prange T, Kennard O, Nature. 1989 Jan 12;337(6203):190-2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2911354 2911354]
+High-pressure protein crystallography (HPPX): instrumentation, methodology and results on lysozyme crystals., Fourme R, Kahn R, Mezouar M, Girard E, Hoerentrup C, Prange T, Ascone I, J Synchrotron Radiat. 2001 Sep 1;8(Pt 5):1149-56. Epub 2001 Aug 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11524565 11524565]
+High pressure macromolecular crystallography: the 140-MPa crystal structure at 2.3 A resolution of urate oxidase, a 135-kDa tetrameric assembly., Colloc'h N, Girard E, Dhaussy AC, Kahn R, Ascone I, Mezouar M, Fourme R, Biochim Biophys Acta. 2006 Mar;1764(3):391-7. Epub 2006 Jan 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16478683 16478683]
+Crystal structure of hen egg-white lysozyme at a hydrostatic pressure of 1000 atmospheres., Kundrot CE, Richards FM, J Mol Biol. 1987 Jan 5;193(1):157-70. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/3586017 3586017]
 [[Category: Fourme, R.]]
 [[Category: Girard, E.]]
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 [[Category: Dna]]
 [[Category: High pressure]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 13:19:18 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 14:29:32 2008''