Goodsell Sandbox: Difference between revisions
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{{STRUCTURE_1wsu | PDB=1wsu | SCENE=Goodsell_Sandbox/1wsu-recognition1/ | {{STRUCTURE_1wsu | PDB=1wsu | SCENE=Goodsell_Sandbox/1wsu-recognition1/3 }} | ||
Molecular Recognition in SelB | Molecular Recognition in SelB | ||
Elongation factor SelB uses several methods to recognize the selenocysteine insertion sequence found in messenger RNA. The insertion sequence forms a hairpin loop with an unstacked guanine base in the loop. This guanine forms | Elongation factor SelB uses several methods to recognize the selenocysteine insertion sequence found in messenger RNA. The insertion sequence forms a hairpin loop with an unstacked guanine base in the loop. This guanine forms | ||
<scene name='Goodsell_Sandbox/1wsu-recognition1/ | <scene name='Goodsell_Sandbox/1wsu-recognition1/3'>specific hydrogen bonds with the protein and with two bridging water molecules (shown in cyan in the jmol).</scene> | ||
The planar base is also sandwiched between | The planar base is also sandwiched between | ||
<scene name='Goodsell_Sandbox/1wsu-recognition2/1'>three amino acids</scene>in the protein, which form a tight hydrophobic pocket. This is best seen using a | <scene name='Goodsell_Sandbox/1wsu-recognition2/1'>three amino acids</scene>in the protein, which form a tight hydrophobic pocket. This is best seen using a | ||
Revision as of 21:18, 15 July 2008
Molecular Recognition in SelB Elongation factor SelB uses several methods to recognize the selenocysteine insertion sequence found in messenger RNA. The insertion sequence forms a hairpin loop with an unstacked guanine base in the loop. This guanine forms The planar base is also sandwiched between in the protein, which form a tight hydrophobic pocket. This is best seen using a The overall shape of the hairpin is recognized by contacts with several In particular, notice the intimate contact formed by both the charged nitrogen and hydrophobic carbon chain of