9gaa: Difference between revisions

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-[[Image:9gaa.gif|left|200px]]
+{{Seed}}
+[[Image:9gaa.png|left|200px]]
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 {{STRUCTURE_9gaa|  PDB=9gaa  |  SCENE=  }}
-'''PRECURSOR OF THE T152A MUTANT GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM'''
+===PRECURSOR OF THE T152A MUTANT GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM===
-==Overview==
+<!--
-A variety of proteins, including glycosylasparaginase, have recently been found to activate functions by self-catalyzed peptide bond rearrangements from single-chain precursors. Here we present the 1.9 A crystal structures of glycosylasparaginase precursors that are able to autoproteolyze via an N --&gt; O acyl shift. Several conserved residues are aligned around the scissile peptide bond that is in a highly strained trans peptide bond configuration. The structure illustrates how a nucleophilic side chain may attack the scissile peptide bond at the immediate upstream backbone carbonyl and provides an understanding of the structural basis for peptide bond cleavage via an N --&gt; O or N --&gt; S acyl shift that is used by various groups of intramolecular autoprocessing proteins.
+The line below this paragraph, {{ABSTRACT_PUBMED_10490104}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 10490104 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_10490104}}
 ==About this Structure==
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 [[Category: N-terminal nucleophile hydrolase]]
 [[Category: Precursor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 22:52:52 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Jul 11 12:56:09 2008''