4i1b: Difference between revisions

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-[[Image:4i1b.jpg|left|200px]]
+{{Seed}}
+[[Image:4i1b.png|left|200px]]
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 {{STRUCTURE_4i1b|  PDB=4i1b  |  SCENE=  }}
-'''FUNCTIONAL IMPLICATIONS OF INTERLEUKIN-1BETA BASED ON THE THREE-DIMENSIONAL STRUCTURE'''
+===FUNCTIONAL IMPLICATIONS OF INTERLEUKIN-1BETA BASED ON THE THREE-DIMENSIONAL STRUCTURE===
-==Overview==
+<!--
-The molecular structure of interleukin-1 beta, a hormone-like cytokine with roles in several disease processes, has been determined at 2.0 A resolution and refined to a crystallographic R-factor of 0.19. The framework of this molecule consists of 12 antiparallel beta-strands exhibiting pseudo-3-fold symmetry. Six of the strands make up a beta-barrel with polar residues concentrated at either end. Analysis of the three-dimensional structure, together with results from site-directed mutagenesis and biochemical and immunological studies, suggest that the core of the beta-barrel plays an important functional role. A large patch of charged residues on one end of the barrel is proposed as the binding surface with which IL-1 interacts with its receptor.
+The line below this paragraph, {{ABSTRACT_PUBMED_1553379}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 1553379 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_1553379}}
 ==About this Structure==
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 [[Category: Veerapandian, B.]]
 [[Category: Cytokine]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 22:25:31 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul  3 13:41:37 2008''