4gsp: Difference between revisions

Revision as of 13:39, 3 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:4gsp.png

Template:STRUCTURE 4gsp

RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS + 3'-GMP, 7 DAYSRIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS + 3'-GMP, 7 DAYS

Template:ABSTRACT PUBMED 9546218

About this StructureAbout this Structure

4GSP is a Single protein structure of sequence from Aspergillus oryzae. Full crystallographic information is available from OCA.

ReferenceReference

Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography., Zegers I, Loris R, Dehollander G, Fattah Haikal A, Poortmans F, Steyaert J, Wyns L, Nat Struct Biol. 1998 Apr;5(4):280-3. PMID:9546218

Page seeded by OCA on Thu Jul 3 13:39:35 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:4gsp.jpg|left|200px]]
+{{Seed}}
+[[Image:4gsp.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_4gsp|  PDB=4gsp  |  SCENE=  }}
-'''RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS + 3'-GMP, 7 DAYS'''
+===RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS + 3'-GMP, 7 DAYS===
-==Overview==
+<!--
-Here we present a time-resolved crystallographic analysis of the hydrolysis of exo (Sp) guanosine 2',3'-cyclophosphorothioate by RNase T1. The use of a slow substrate and fast crystallization methods made it possible to perform the study with conventional data-collection techniques. The results support the idea that the hydrolysis reaction proceeds through a mechanism that is the inverse of the transesterification reaction. In addition, the structures provide an explanation for the differential behavior of RNase T1 towards exo- and endo-cyclic thiophosphates.
+The line below this paragraph, {{ABSTRACT_PUBMED_9546218}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 9546218 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_9546218}}
 ==About this Structure==
@@ Line 26: / Line 30: @@
 [[Category: Endoribonuclease]]
 [[Category: Hydrolase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 22:24:48 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul  3 13:39:35 2008''