1mhc: Difference between revisions

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-[[Image:1mhc.gif|left|200px]]
+{{Seed}}
+[[Image:1mhc.png|left|200px]]
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 {{STRUCTURE_1mhc|  PDB=1mhc  |  SCENE=  }}
-'''MODEL OF MHC CLASS I H2-M3 WITH NONAPEPTIDE FROM RAT ND1 REFINED AT 2.3 ANGSTROMS RESOLUTION'''
+===MODEL OF MHC CLASS I H2-M3 WITH NONAPEPTIDE FROM RAT ND1 REFINED AT 2.3 ANGSTROMS RESOLUTION===
-==Overview==
+<!--
-H2-M3 is a class Ib MHC molecule of the mouse with a 10(4)-fold preference for binding N-formylated peptides. To elucidate the basis of this unusual specificity, we expressed and crystallized a soluble form of M3 with a formylated nonamer peptide, fMYFINILTL, and determined the structure by X-ray crystallography. M3, refined at 2.1 A resolution, resembles class la MHC molecules in its overall structure, but differs in the peptide-binding groove. The A pocket, which usually accommodates the free N-terminus of a bound peptide, is closed, and the peptide is shifted one residue, such that the P1 side chain is lodged in the B pocket. The formyl group is coordinated by His-9 and a bound water on the floor of the groove.
+The line below this paragraph, {{ABSTRACT_PUBMED_7664344}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 7664344 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_7664344}}
 ==About this Structure==
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 [[Category: Wang, C R.]]
 [[Category: Histocompatibility antigen/peptide]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 01:01:31 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 23:57:43 2008''