1mdo: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1mdo.gif|left|200px]]
+{{Seed}}
+[[Image:1mdo.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_1mdo|  PDB=1mdo  |  SCENE=  }}
-'''Crystal structure of ArnB aminotransferase with pyridomine 5' phosphate'''
+===Crystal structure of ArnB aminotransferase with pyridomine 5' phosphate===
-==Overview==
+<!--
-Lipid A modification with 4-amino-4-deoxy-L-arabinose confers on certain pathogenic bacteria, such as Salmonella, resistance to cationic antimicrobial peptides, including those derived from the innate immune system. ArnB catalysis of amino group transfer from glutamic acid to the 4"-position of a UDP-linked ketopyranose molecule to form UDP-4-amino-4-deoxy-L-arabinose represents a key step in the lipid A modification pathway. Structural and functional studies of the ArnB aminotransferase were undertaken by combining X-ray crystallography with biochemical analyses. High-resolution crystal structures were solved for two native forms and one covalently inhibited form of S. typhimurium ArnB. These structures permitted identification of key residues involved in substrate binding and catalysis, including a rarely observed nonprolyl cis peptide bond in the active site.
+The line below this paragraph, {{ABSTRACT_PUBMED_12429098}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 12429098 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_12429098}}
 ==About this Structure==
@@ Line 36: / Line 40: @@
 [[Category: Wright, T.]]
 [[Category: Type 1 aminotransferase fold]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 00:55:02 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 23:44:41 2008''