1ji4: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
No edit summary
No edit summary
Line 1: Line 1:
[[Image:1ji4.gif|left|200px]]
{{Seed}}
[[Image:1ji4.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1ji4|  PDB=1ji4  |  SCENE=  }}  
{{STRUCTURE_1ji4|  PDB=1ji4  |  SCENE=  }}  


'''NAP protein from helicobacter pylori'''
===NAP protein from helicobacter pylori===




==Overview==
<!--
Helicobacter pylori is a major human pathogen associated with severe gastroduodenal diseases, including ulcers and cancers. An H.pylori protein that is highly immunogenic in humans and mice has been identified recently. This protein has been termed HP-NAP, due to its ability of activating neutrophils. In order to achieve a molecular understanding of its unique immunogenic and pro-inflammatory properties, we have determined its three-dimensional structure. Its quaternary structure is similar to that of the dodecameric bacterial ferritins (Dps-like family), but it has a different surface potential charge distribution. This is due to the presence of a large number of positively charged residues, which could well account for its unique ability in activating human leukocytes.
The line below this paragraph, {{ABSTRACT_PUBMED_12368104}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 12368104 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_12368104}}


==About this Structure==
==About this Structure==
Line 32: Line 36:
[[Category: Dodecamer]]
[[Category: Dodecamer]]
[[Category: Four-helix bundle]]
[[Category: Four-helix bundle]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 21:15:05 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:16:50 2008''

Revision as of 20:16, 1 July 2008

File:1ji4.png

Template:STRUCTURE 1ji4

NAP protein from helicobacter pyloriNAP protein from helicobacter pylori

Template:ABSTRACT PUBMED 12368104

About this StructureAbout this Structure

1JI4 is a Single protein structure of sequence from Helicobacter pylori. Full crystallographic information is available from OCA.

ReferenceReference

Structure of the neutrophil-activating protein from Helicobacter pylori., Zanotti G, Papinutto E, Dundon W, Battistutta R, Seveso M, Giudice G, Rappuoli R, Montecucco C, J Mol Biol. 2002 Oct 11;323(1):125-30. PMID:12368104

Page seeded by OCA on Tue Jul 1 20:16:50 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA