1iv5: Difference between revisions

Revision as of 14:03, 1 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:1iv5.png

Template:STRUCTURE 1iv5

New Crystal Form of Human CD81 Large Extracellular Loop.New Crystal Form of Human CD81 Large Extracellular Loop.

Template:ABSTRACT PUBMED 12437138

About this StructureAbout this Structure

1IV5 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Subunit association and conformational flexibility in the head subdomain of human CD81 large extracellular loop., Kitadokoro K, Ponassi M, Galli G, Petracca R, Falugi F, Grandi G, Bolognesi M, Biol Chem. 2002 Sep;383(9):1447-52. PMID:12437138

Page seeded by OCA on Tue Jul 1 14:03:29 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''New Crystal Form of Human CD81 Large Extracellular Loop.'''
+===New Crystal Form of Human CD81 Large Extracellular Loop.===
-==Overview==
+<!--
-The large extracellular loop of human CD81, a tetraspanin mediating hepatitis C virus envelope protein E2 binding to human cells, has been crystallized in a hexagonal form. The three-dimensional structure, solved and refined at 2.6 A resolution (R-factor = 22.8%), shows that the protein adopts a dimeric assembly, based on an association interface built up by tetraspanin-conserved residues. Structural comparisons with the tertiary structure of human CD81 large extracellular loop, previously determined in a different crystal form, show marked conformational fluctuations in the molecular regions thought to be involved in binding to the viral protein, suggesting rules for recognition and assembly within the tetraspan web.
+The line below this paragraph, {{ABSTRACT_PUBMED_12437138}}, adds the Publication Abstract to the page
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+{{ABSTRACT_PUBMED_12437138}}
 ==About this Structure==
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 [[Category: Alpha domain]]
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-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 20:27:28 2008''
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