1ire: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:
[[Image:1ire.gif|left|200px]]
{{Seed}}
[[Image:1ire.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1ire|  PDB=1ire  |  SCENE=  }}  
{{STRUCTURE_1ire|  PDB=1ire  |  SCENE=  }}  


'''Crystal Structure of Co-type nitrile hydratase from Pseudonocardia thermophila'''
===Crystal Structure of Co-type nitrile hydratase from Pseudonocardia thermophila===




==Overview==
<!--
The crystal structure of cobalt-containing nitrile hydratase from Pseudonocardia thermophila JCM 3095 at 1.8 A resolution revealed the structure of the noncorrin cobalt at the catalytic center. Two cysteine residues (alphaCys(111) and alphaCys(113)) coordinated to the cobalt were posttranslationally modified to cysteine-sulfinic acid and to cysteine-sulfenic acid, respectively, like in iron-containing nitrile hydratase. A tryptophan residue (betaTrp(72)), which may be involved in substrate binding, replaced the tyrosine residue of iron-containing nitrile hydratase. The difference seems to be responsible for the preference for aromatic nitriles rather than aliphatic ones of cobalt-containing nitrile hydratase.
The line below this paragraph, {{ABSTRACT_PUBMED_11700034}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11700034 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_11700034}}


==About this Structure==
==About this Structure==
Line 33: Line 37:
[[Category: Non-corrin cobalt]]
[[Category: Non-corrin cobalt]]
[[Category: Post-translational modification]]
[[Category: Post-translational modification]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 20:19:18 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 13:51:53 2008''

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA