1het: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-[[Image:1het.gif|left|200px]]
+{{Seed}}
+[[Image:1het.png|left|200px]]
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 {{STRUCTURE_1het|  PDB=1het  |  SCENE=  }}
-'''ATOMIC X-RAY STRUCTURE OF LIVER ALCOHOL DEHYDROGENASE CONTAINING A HYDROXIDE ADDUCT TO NADH'''
+===ATOMIC X-RAY STRUCTURE OF LIVER ALCOHOL DEHYDROGENASE CONTAINING A HYDROXIDE ADDUCT TO NADH===
-==Overview==
+<!--
-Atomic (1 A) resolution x-ray structures of horse liver alcohol dehydrogenase in complex with NADH revealed the formation of an adduct in the active site between a metal-bound water and NADH. Furthermore, a pronounced distortion of the pyridine ring of NADH was observed. A series of quantum chemical calculations on the water-nicotinamide adduct showed that the puckering of the pyridine ring in the crystal structures can only be reproduced when the water is considered a hydroxide ion. These observations provide fundamental insight into the enzymatic activation of NADH for hydride transfer.
+The line below this paragraph, {{ABSTRACT_PUBMED_11134046}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 11134046 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_11134046}}
 ==About this Structure==
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 [[Category: Merli, A.]]
 [[Category: Morris, R J.]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 18:46:39 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 08:05:30 2008''