1gnh: Difference between revisions

Revision as of 05:33, 1 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:1gnh.png

1gnh, resolution 3.00Å ()

Ligands:

Structural annotation:
Resources:	CATH : 1Gnha00, 1Gnhb00, 1Gnhc00, 1Gnhd00, 1Gnhe00, 1Gnhf00, 1Gnhg00, 1Gnhh00, 1Gnhi00, 1Gnhj00 InterPro : Ipr001759, Ipr013320, Ipr008985 Pfam : PF00354 SCOP : d1gnha_, d1gnhb_, d1gnhc_, d1gnhd_, d1gnhe_, d1gnhf_, d1gnhg_, d1gnhh_, d1gnhi_, d1gnhj_ UniProt : P02741

Functional annotation:
Cellular component:	extracellular region
Biological process:	inflammatory response acute-phase response
Molecular function:	binding calcium ion binding metal ion binding

Evolutionary conservation:

Toggle Conservation Colors:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

HUMAN C-REACTIVE PROTEINHUMAN C-REACTIVE PROTEIN

Template:ABSTRACT PUBMED 8599761

About this StructureAbout this Structure

1GNH is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Three dimensional structure of human C-reactive protein., Shrive AK, Cheetham GM, Holden D, Myles DA, Turnell WG, Volanakis JE, Pepys MB, Bloomer AC, Greenhough TJ, Nat Struct Biol. 1996 Apr;3(4):346-54. PMID:8599761

Page seeded by OCA on Tue Jul 1 05:33:37 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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+===HUMAN C-REACTIVE PROTEIN===
-==Overview==
+<!--
-The structure of the classical acute phase reactant human C-reactive protein provides evidence that phosphocholine binding is mediated through calcium and a hydrophobic pocket centred on Phe 66. The residue Glu 81 is suitably positioned to interact with the choline group. A cleft on the pentameric face opposite to that containing the calcium site may have an important functional role. The structure provides insights into the molecular mechanisms by which this highly conserved plasma protein, for which no polymorphism or deficiency state is known, may exert its biological role.
+The line below this paragraph, {{ABSTRACT_PUBMED_8599761}}, adds the Publication Abstract to the page
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+{{ABSTRACT_PUBMED_8599761}}
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 [[Category: Acute-phase reactant]]
 [[Category: Pentraxin]]
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