1elq: Difference between revisions

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-[[Image:1elq.gif|left|200px]]
+{{Seed}}
+[[Image:1elq.png|left|200px]]
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 {{STRUCTURE_1elq|  PDB=1elq  |  SCENE=  }}
-'''CRYSTAL STRUCTURE OF THE CYSTINE C-S LYASE C-DES'''
+===CRYSTAL STRUCTURE OF THE CYSTINE C-S LYASE C-DES===
-==Overview==
+<!--
-FeS clusters are versatile cofactors of a variety of proteins, but the mechanisms of their biosynthesis are still unknown. The cystine C-S lyase from Synechocystis has been identified as a participant in ferredoxin FeS cluster formation. Herein, we report on the crystal structure of the lyase and of a complex with the reaction products of cystine cleavage at 1.8- and 1.55-A resolution, respectively. The sulfur-containing product was unequivocally identified as cysteine persulfide. The reactive persulfide group is fixed by a hydrogen bond to His-114 in the center of a hydrophobic pocket and is thereby shielded from the solvent. Binding and stabilization of the cysteine persulfide represent an alternative to the generation of a protein-bound persulfide by NifS-like proteins and point to the general importance of persulfidic compounds for FeS cluster assembly.
+The line below this paragraph, {{ABSTRACT_PUBMED_10760256}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 10760256 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_10760256}}
 ==About this Structure==
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 [[Category: Pyridoxal 5'-phosphate]]
 [[Category: Thiocysteine]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 15:15:15 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 00:57:02 2008''