1dc0: Difference between revisions

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{{STRUCTURE_1dc0|  PDB=1dc0  |  SCENE=  }}  
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'''CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG'''
===CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG===




==Overview==
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The DNA dodecamer CATGGGCCCATG in a crystal structure of resolution 1.3 A has a conformation intermediate between A and B DNA. This trapping of a stable intermediate suggests that the A and B DNA families are not discrete, as previously believed. The structure supports a base-centered rather than a backbone-centered mechanism for the A &lt;--&gt; B transition mediated by guanine tracts. Interconversion between A and B DNA provides another means for regulating protein-DNA recognition.
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==About this Structure==
==About this Structure==
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[[Category: B-dna]]
[[Category: B-dna]]
[[Category: Intermediate]]
[[Category: Intermediate]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 13:40:25 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:48:01 2008''

Revision as of 22:48, 30 June 2008

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Template:STRUCTURE 1dc0

CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATGCRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG

Template:ABSTRACT PUBMED 10688897

About this StructureAbout this Structure

Full crystallographic information is available from OCA.

ReferenceReference

The structure of a stable intermediate in the A <--> B DNA helix transition., Ng HL, Kopka ML, Dickerson RE, Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2035-9. PMID:10688897

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