1d7q: Difference between revisions

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-[[Image:1d7q.jpg|left|200px]]
+{{Seed}}
+[[Image:1d7q.png|left|200px]]
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 {{STRUCTURE_1d7q|  PDB=1d7q  |  SCENE=  }}
-'''HUMAN TRANSLATION INITIATION FACTOR EIF1A'''
+===HUMAN TRANSLATION INITIATION FACTOR EIF1A===
-==Overview==
+<!--
-The translation initiation factor eIF1A is necessary for directing the 43S preinitiation complex from the 5' end of the mRNA to the initiation codon in a process termed scanning. We have determined the solution structure of human eIF1A, which reveals an oligonucleotide-binding (OB) fold and an additional domain. NMR titration experiments showed that eIF1A binds single-stranded RNA oligonucleotides in a site-specific, but non-sequence-specific manner, hinting at an mRNA interaction rather than specific rRNA or tRNA binding. The RNA binding surface extends over a large area covering the canonical OB fold binding site as well as a groove leading to the second domain. Site-directed mutations at multiple positions along the RNA-binding surface were defective in the ability to properly assemble preinitiation complexes at the AUG codon in vitro.
+The line below this paragraph, {{ABSTRACT_PUBMED_10678173}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 10678173 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_10678173}}
 ==About this Structure==
-D7Q is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D7Q OCA].
+D7Q is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D7Q OCA].
 ==Reference==
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 [[Category: Ob-fold]]
 [[Category: Rna-binding protein]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 13:32:34 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:38:21 2008''