1d64: Difference between revisions

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-[[Image:1d64.gif|left|200px]]
+{{Seed}}
+[[Image:1d64.png|left|200px]]
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 {{STRUCTURE_1d64|  PDB=1d64  |  SCENE=  }}
-'''CRYSTAL STRUCTURE OF A PENTAMIDINE-OLIGONUCLEOTIDE COMPLEX: IMPLICATIONS FOR DNA-BINDING PROPERTIES'''
+===CRYSTAL STRUCTURE OF A PENTAMIDINE-OLIGONUCLEOTIDE COMPLEX: IMPLICATIONS FOR DNA-BINDING PROPERTIES===
-==Overview==
+<!--
-The crystal structure of the complex formed between the dodecanucleotide d(CGCGAATTCGCG)2 and the drug pentamidine, which is active against the Pneumocystis carinii pathogen in AIDS patients, has been determined to a resolution of 2.1 A and an R-factor of 19.4%. Analysis of the structure has shown the drug to be bound in the 5'-AATT minor groove region of the duplex, with the amidinium groups H-bonded to adenine N3 atoms in an interstrand manner. The drug molecule adopts an extended conformation, and the immediate binding site spans four base pairs. Structural details of the drug-DNA interactions are discussed, and comparison is made with the dodecamer complex of the structurally similar berenil ligand.
+The line below this paragraph, {{ABSTRACT_PUBMED_1643044}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 1643044 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_1643044}}
 ==About this Structure==
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 [[Category: Complexed with drug]]
 [[Category: Double helix]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 13:29:36 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:30:59 2008''